Why Selenium Is Important For The Immune System And What We Do Differently

As you may remember from our articles on copper, boron or vitamins C & E, antioxidant enzymes are important for the immune system, a long life and a healthy metabolism. Antioxidant enzymes are important for the killing of microbes (which includes bacteria and viruses) (1). Selenium helps produce an antioxidant enzyme, which is why it is deemed essential for the immune system (2). It is well documented that selenium deficiency is associated with higher susceptibility to RNA viral infections (such as COVID-19) and more severe disease outcomes (3). For example, an 80% reduction in the number of deaths from hantavirus was observed with selenium supplementation (4).

A study on AIDS/HIV-related death found an inverse correlation between the death rates and selenium intake, whereby more selenium was related to less death (5). Clinical trials of selenium in AIDS/HIV have found benefits (6) (7) (8) (9).

For COVID-19, a study looking at 17 Chinese cities found that the higher the selenium levels of the population, the faster their recovery rates from the disease were (10). In fact, the city with the highest selenium levels had a three times faster recovery rate (10). This implies having higher than normal selenium levels, may offer more protection from the harmful effects of viral infections (11).

A German study found there was a strong correlation between coronavirus outcome and selenium levels in hospitalized patients. 65% of those who died had low selenium levels compared to 39% of those who survived (12). In our opinion this may not seem like much, but it definitely supports the idea that if one were to have multiple nutrient deficiencies, these could greatly contribute towards a higher risk of death. Elderly people seem to be at higher risk of selenium deficiency (13), which may partly explain the link between being old and experiencing a poor COVID-19 outcome (Side note: As we explain in our zinc article, low zinc may also explain the link between age and COVID-19 mortality). The elderly people with the highest levels of selenium were also more likely to be fit and healthy (14).

In many European populations, people do not consume enough selenium to meet the minimum requirement of 70micrograms/day (15). It is estimated that up to 14% of people worldwide (about 1 billion) are not consuming this minimum requirement (16). This is not taking into account that optimal amounts of selenium for the immune system may be higher than 70micrograms/day. The Chinese city with the fastest recovery rates from COVID-19 had an estimated intake of 550 micrograms (17). 550micrograms is still above the upper limit intake of 400micrograms, so we do not suggest aiming for such a high intake long term. Intakes of over 400micrograms may cause depletions of other nutrients long term (24).

We have opted for 200micrograms of selenium because over a period of 2-4 years trials have shown this level to be safe and effective for the immune system of HIV patients (7) (8) (9) and the elderly. Giving 200micrograms to the elderly was found to reduce viral infection rates and deaths from cardiovascular disease (18) (19).

When it comes to supplementation organic forms of selenium such as selenomethionine are retained better than inorganic forms of selenium (20) (21) (22). They have also been found to be safer (23). Most multivitamins will contain the inorganic forms, whereas we have decided to use what seem to be the safer, better retained version of selenium. This is also why we use the organic forms of copper, zinc and iron (as you can read in our articles).

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For more information about how taking the ThinkPharm Formula would improve your life check out our other articles about how it was designed.

For a vitamin supplement that doesn’t profit from your misinformation and actually tries to improve your health, get your hands on the ThinkPharm Formula. Check out the formula on our product page.

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Disclaimer: Food supplements are intended to correct nutritional deficiencies, maintain an adequate intake of certain nutrients, or to support specific physiological functions. The ThinkPharm Formula (or any other food supplement) is not a medicine and therefore cannot and does not claim to treat or prevent disease. All content on this website is for educational purposes only and does not constitute medical advice. None of the scientific studies quoted on this website qualify as proof or implication that ThinkPharm Health's supplements treat or prevent disease. Findings of scientific studies do not always represent reality. It is always difficult for scientific studies to reach accurate conclusions regarding nutrition and its relationship to diseases. Please consult your healthcare professional before making any significant changes to your diet and lifestyle. ThinkPharm Health is not liable for risks or issues associated with using or acting on information from this website.

 

 

Health claims you can trust

All the health claims that are listed below and on our supplement package have been authorised by the European Food Safety Authority (EFSA).

The EFSA reviews the evidence on different vitamins and minerals to ensure that there is enough evidence to make certain health claims.

Although the UK is no longer part of the EU it still relies on the EFSA's judgement for legally allowed claims.

Below are all the health claims we are allowed to use for the ThinkPharm Formula based on the abundance of evidence.

Over 40 EFSA authorised health claims

Hair, skin and nails

Contributes to the maintenance of normal hair: Zinc, Selenium, Biotin (B7)

Contributes to the maintenance of normal skin: Zinc, Riboflavin (B2), Niacin (B3), Iodine, Biotin (B7)

Contributes to the maintenance of normal nails: Zinc, Selenium

Contributes to normal hair and skin pigmentation: Copper

Bones, joints and muscle function

Contributes to the maintenance of normal bones: Vitamin D, Vitamin K, Zinc

Contributes to the maintenance of normal muscle function: Vitamin D

Contributes to the maintenance of normal teeth: Vitamin D

Contributes to the maintenance of normal connective tissues (tendons, ligaments and cartilage): Copper

Contributes to normal absorption/utilisation of calcium and phosphorus: Vitamin D

Contributes to normal blood calcium levels: Vitamin D

Heart health

Contributes to normal heart function: Thiamin (B1)

Metabolism

Contributes to the normal production of thyroid hormones: Iodine

Contributes to normal thyroid function: Iodine, Selenium

Contributes to the maintenance of normal blood glucose levels: Chromium

Contributes to normal macronutrient metabolism: Zinc, Chromium, Biotin (B7)

Contributes to normal protein and glycogen metabolism: Vitamin B6

Contributes to normal amino acid synthesis: Folate (B9)

Contributes to normal cysteine synthesis: Vitamin B6

Healthy cells

Contributes to the protection of cells from oxidative stress: Zinc, Copper, Selenium, Riboflavin (B2)

Has a role in the process of cell division: Vitamin D, Folate (B9), Vitamin B12

Contributes to normal DNA synthesis: Zinc, Folate (B9)

Contributes to normal homocysteine metabolism: Vitamin B6, Vitamin B12, Folate (B9)

Cognitive function

Contributes to normal cognitive function: Zinc, Iodine

Contributes to normal mental performance: Pantothenic Acid (B5)

Contributes to normal synthesis of certain neurotransmitters: Pantothenic Acid (B5)

Mental Health

Contributes to normal psychological function: Thiamin (B1), Niacin (B3), Vitamin B6, Folate (B9), Biotin (B7), Vitamin B12

Contributes to the normal functioning of the nervous system: Thiamin (B1), Riboflavin (B2), Niacin (B3), Vitamin B6, Biotin (B7), Copper, Iodine

Energy levels

Contributes to the reduction of tiredness and fatigue: Riboflavin (B2), Niacin (B3), Pantothenic Acid (B5), Folate (B9), Vitamin B6, Vitamin B12

Contributes to normal energy-yielding metabolism: Thiamin (B1), Riboflavin (B2), Niacin (B3), Pantothenic Acid (B5), Vitamin B6, Biotin (B7), Vitamin B12, Copper, Iodine

Contributes to normal iron transport in the body: Copper

Contributes to normal iron metabolism: Riboflavin (B2), Copper

Contributes to normal red blood cell formation: Riboflavin (B2), Vitamin B6, Folate (B9), Vitamin B12

Contributes to normal blood formation: Folate (B9)

Immune system

Contributes to the normal function of the immune system: Vitamin D, Zinc, Selenium, Copper, Folate (B9), Vitamin B6, Vitamin B12

Contributes to the maintenance of normal mucous membranes: Riboflavin (B2), Niacin (B3), Biotin (B7)

Vision (eye health)

Contributes to the maintenance of normal vision: Zinc, Riboflavin (B2)

Reproductive and hormonal health

Contributes to regulation of hormonal activity: Vitamin B6

Contributes to normal synthesis and metabolism of steroid hormones, vitamin D, and some neurotransmitters: Pantothenic Acid (B5)

Contributes to normal fertility and reproduction: Zinc

Contributes to maternal tissue growth during pregnancy: Folate (B9)

Contributes to the maintenance of normal serum testosterone concentrations: Zinc

Contributes to normal spermatogenesis: Selenium

Digestive health

Contributes to the maintenance of normal mucous membranes: Riboflavin (B2), Niacin (B3), Biotin (B7)

Please note, there are no EFSA authorised claims for probiotics.
The amount of iron in the ThinkPharm Formula is too small for a legally allowed claim. We have mainly added it with the intention of avoiding potential depletions caused by other vitamins and minerals in the formula. For more information as to why we have mainly excluded iron from our supplement, please see our article: The Iron Controversy – What We Do Different About Iron